February 8, 2023 | Volume V, Issue 3
Medical Class of 2025 Celebrates Completion of Foundations Curriculum
Faculty, staff, and students gathered in the Hoehl Gallery in the Larner College of Medicine’s Health Science Research Facility to honor a milestone in the Class of 2025’s medical education journey at the Foundations Awards Celebration on January 26, 2023. The annual event marks the medical students’ completion of Foundations – the first level of the Vermont Integrated Curriculum – and recognizes the students’ accomplishments and the teachers and staff who helped them along the way.
Foundations Director Karen Lounsbury, Ph.D., kicked off the event, welcoming attendees to the celebration. Larner Dean Richard Page, M.D., followed with additional remarks, and then Class of 2025 medical student leader Justin Henningsen presented a recap of class members’ medical education journey to date.
Class of ’25 medical students who participated in the presentation of awards included (in order of appearance) Angela Russo, Caitlin Early, M.P.H., Kadi Nguyen, Elizabeth Kelley, Jennifer Toner, Gabriela Sarriera-Valentin, Justin Henningsen, James Fanning, Nic Hutt, Jharna Jahnavi, Ellen Mats, and Taylor Walker. Faculty and staff award presenters included (in order of appearance) Ira Bernstein, M.D., professor and chair of obstetrics, gynecology, and reproductive sciences; Karen George, M.D., M.P.H., associate dean for students; Christina Wojewoda, M.D., associate professor of pathology and laboratory medicine; Shirley McAdam, Standardized Patient educator; and Dr. Lounsbury.
At the close of the awards presentations, Elise Everett, M.D., associate professor of obstetrics, gynecology, and reproductive sciences and level director of clinical clerkship, welcomed the Class of 2025 to Clinical Clerkship – the second level of the Vermont Integrated Curriculum. Class of 2025 medical students are currently preparing to take Step 1 – the first part of the United States Medical Licensing Examination – and will begin the clinical portion of their education in March 2023.
Read the full article with names of awards and award recipients.
Pictured above (left to right): Neeki Parsa ’25, winner of the Wellness Award, with Class of 2025 Wellness Committee members Mats, Jahnavi, Walker, and Mimi Falcone (Photo: David Seaver)
UVM Cancer Center to Launch CAR T-Cell Program
Novel therapy turns patient’s T-cells into ‘personalized cancer-killing machines’
Starting this
spring, the UVM Cancer Center will offer a novel, highly effective form of
cancer treatment called CAR T-cell therapy. The UVM Cancer Center will be the
only health care institution in Vermont and northern New York to provide this
treatment.
CAR (chimeric
antigen receptor) T-cell therapy, or CART as it is known, is a promising
treatment that harnesses the power of the body’s own immune system to target
cancer cells. Normally, our T cells attack foreign invaders like cold viruses,
fighting off infections that could make us sick. While T cells can kill off
many kinds of cancers before they become established, cancer that is developed
and diagnosable is able to evade the immune system.
But maybe not for
much longer.
CAR T-cell therapy
re-engineers a patient’s own T cells to recognize a specific cancer, turning
the re-programmed T cells into personalized cancer-killing machines.
Currently used to
treat lymphomas, leukemia, and multiple myeloma, this leading-edge therapy
gives patients another option when chemotherapy or other current treatments
fail. The therapy also offers great promise for someday treating patients with
breast, prostate, and other types of cancers.
“It’s unlike any other therapy that’s ever been given before,” says James Gerson, M.D., assistant professor of medicine at the Larner College of Medicine, who joined the UVM Cancer Center in September 2022 and will direct the new CAR T-Cell program. “This therapy is a living, breathing treatment that goes back into the patient and lives with them for years. It’s exciting to be starting a new CAR T-cell program here at UVM, and to offer this potentially curative therapy to patients in the region.”
Carney Comments on Confronting Medical Misinformation
Below is an
edited excerpt from a commentary written by Jan Carney, M.D., M.P.H.,
associate dean for public health and health policy and professor of medicine at
the Larner College of Medicine. Dr. Carney is board-certified in both internal
medicine and preventive medicine and served as Vermont’s Commissioner of Health
under three gubernatorial administrations championing improvements in
children’s health insurance, preventing teen smoking, and improving cancer
screening. She was recently awarded the UVM President’s Distinguished
University Citizenship and Service Award for her innovative teaching, creative
leadership, and service to the UVM community.
The public
increasingly has access to an explosion of new scientific and medical
information, and people are much more likely to use social media as part of
their search for health information.
The spread of
misinformation was so extreme during the pandemic – from unproven remedies to
vaccine myths – that the U.S. Surgeon General launched a campaign against health misinformation
for the public. From a public health perspective, shouldn’t we leverage
opportunities to promote high-quality health information available to people
through internet sources and social media? On a population level, making it
easy for people to find reliable health information online would go a long way toward
improving health.
In late August 2022, California legislators passed
a law allowing their medical regulatory board to discipline physicians,
defining “false or misleading” medical information about COVID-19 vaccines and
treatments as “unprofessional conduct.” Earlier, in 2021, the Federation of State
Medical Boards (FSMB) publicly reminded physicians that
because of their ethical and professional responsibilities, high level of
public trust, and risks to patients, spreading COVID-19 vaccine misinformation
could potentially result in disciplinary measures to their medical license. By the end of November 2022, California’s
law – before it took effect – already had two legal challenges, and on January
26, 2023, a federal judge halted the law’s enforcement. It is unclear
yet what the outcome of the new California law will be.
It is important to identify where people get health and scientific information and whom they trust, and to address challenges of improving health literacy on a patient and population level. Health literacy is a skill that takes practice, and as scientists, health care, and public health professionals, we can present – at every opportunity – clear, accurate, and easily understandable health information.
Pictured above: Dr. Carney (Photo: Brent Harrewyn)
UVM’s Dana Medical Library now offers Geographic Information Services support for faculty, staff, and students, which includes assistance with finding geographic data or analyzing data that is associated with locations. More information about GIS Support and Consulting Services can be found here.
Learn about UVM’s first African American medical students in “The Forerunners,” from the current issue of Vermont Medicine magazine.
Accolades & Appointments
Toishi Sharma, M.B.B.S., a cardiovascular fellow in the Department of Medicine, won first place in the Cardiovascular Research Institute (CVRI) of Vermont’s fourth annual Viridis Montis Early Career Investigator Challenge. Dr. Sharma receives a $5,000 prize for her research project titled “Platelet FcyRIIa expression, a powerful marker of cardiovascular risk in women,” which she conducted with her mentor David Schneider, M.D., professor of medicine and director of the Division of Cardiovascular Medicine. The merit-based competition highlights outstanding cardiovascular research being conducted by early-career investigators from across the University of Vermont (UVM), UVM Larner College of Medicine, and UVM Health Network. Organized by the CVRI Early Career Advisory Committee, the event took place on February 1 in the Larner Classroom. Five finalists delivered oral abstract presentations before a panel of five invited judges that included Noma Anderson, Ph.D., dean of the College of Nursing and Health Sciences; Fabrice Dabertrand, Ph.D., former faculty member in the UVM Department of Pharmacology and current associate professor of anesthesiology at the University of Colorado School of Medicine; Philip Ades, M.D., professor of medicine; Markus Meyer, M.D., adjunct associate professor of medicine and associate professor of medicine at the University of Minnesota; and Diann Gaalema, Ph.D., associate professor of psychiatry. In addition to Sharma, the finalists in the competition were Ryan Hunt, doctoral candidate in the Neuroscience Graduate Program; Aaron Lambert, M.D., general surgery resident; Amreen Mughal, Ph.D., assistant professor of pharmacology; and Samuel Short, Larner Class of 2023 medical student.
The Larner medical Class of 2025 elected Justin Henningsen as the 2023-2024 president-elect of the Medical Student Council, effective March 17, 2023 (Match Day). In addition, current president-elect Elise Prehoda, Class of 2024 medical student, will transition on Match Day into her new role as the 2023-2024 student body and student council president. Henningsen, who previously served as the Medical Student Council’s chair of student leadership, will become student body president and president of the Medical Student Council in 2024-2025 (the Class of 2025’s fourth year).
The Medical Student Council recognizes outgoing Class of 2023 members, including Vinh Le, president, and senior leadership team members Lud Eyasu, Kyle Kellett, and Cyrus Thomas-Walker, for their service to the college and to the medical student body.
Pictured at left: Henningsen (top) and PrehodaSara Tourville, medical student coordinator for the Department of Obstetrics, Gynecology, and Reproductive Sciences, was honored by the Association of Professors of Gynecology and Obstetrics (APGO) with the annual Donna Wachter Clerkship Coordinator Award. The award recognizes an outstanding Ob-Gyn clerkship coordinator as identified by the individual’s department chair. APGO, which represents academic obstetricians-gynecologists throughout the United States and Canada, bestows only one clerkship coordinator award per year. Tourville’s nominators describe her as a team-oriented problem-solver and the driving force behind innovations in the clerkship, frequently championing different systems for tracking student outcomes or aspects of the rotation that could use improvement. “This is an incredible honor, and I’m thankful for the continued support of my department,” Tourville said.
CITATION HIGHLIGHTS
Bates JHT, Kaminsky DA, Garrow OJ, Martin FK, Peters U, Tharp WG, Dixon AE. Lung de-recruitment in the allergic asthma of obesity: evidence from an anatomically based inverse model. J Appl Physiol
(1985). 2023 Feb 1;134(2):356-364. doi: 10.1152/japplphysiol.00540.2022. Epub 2023 Jan 5. PMID: 36603046.
Cipolla MJ, Tremble SM, DeLance N, Johnson AC. Worsened Stroke Outcome in a Model of Preeclampsia is Associated With Poor Collateral Flow and Oxidative Stress. Stroke. 2023 Feb;54(2):354-363. doi: 10.1161/STROKEAHA.122.041637. Epub 2023 Jan 23. PMID: 36689585; PMCID: PMC9888018.
Cipolla MJ. Therapeutic Induction of Collateral Flow. Transl Stroke Res. 2023 Feb;14(1):53-65. doi: 10.1007/s12975-022-01019-2. Epub 2022 Apr 13. PMID: 35416577.
Clayton DA, Eguchi MM, Kerr KF, Miyoshi K, Brunyé TT, Drew T, Weaver DL, Elmore JG. Are Pathologists Self-Aware of Their Diagnostic Accuracy? Metacognition and the Diagnostic Process in Pathology. Med Decis Making. 2023 Feb;43(2):164-174. doi: 10.1177/0272989X221126528. Epub 2022 Sep 20. PMID: 36124966; PMCID: PMC9825636.
Cullen ER, Tariq K, Shore AN, Luikart BW, Weston MC. mTORC2 Inhibition Improves Morphological Effects of PTEN Loss, But Does Not Correct Synaptic Dysfunction or Prevent Seizures. J Neurosci. 2023 Feb 1;43(5):827-845. doi: 10.1523/JNEUROSCI.1354-22.2022. Epub 2022 Dec 16. PMID: 36526374.
Danaher M, Faucett SC, Endres NK, Geeslin AG. Repair of Quadriceps and Patellar Tendon Tears. Arthroscopy. 2023 Feb;39(2):142-144. doi: 10.1016/j.arthro.2022.10.034. Epub 2022 Nov 2. PMID: 36332853.
Dixon AE, Que LG, Kalhan R, Dransfield MT, Rogers L, Gerald LB, Kraft M, Krishnan JA, Johnson O, Hazucha H, Roy G, Holbrook JT, Wise RA. Roflumilast May Increase Risk of Exacerbations When Used to Treat Poorly Controlled Asthma in People with Obesity. Ann Am Thorac Soc. 2023 Feb;20(2):206-214. doi: 10.1513/AnnalsATS.202204-368OC. PMID: 36170654.
Fanning JE, Okamoto LA, Levine EC, McGee SA, Janis JE. Content and Readability of Online Recommendations for Breast Implant Size Selection. Plast Reconstr Surg Glob Open. 2023 Jan 24;11(1):e4787. doi: 10.1097/GOX.0000000000004787. PMID: 36699215; PMCID: PMC9872969.
Fraiman YS, Edwards EM, Horbar JD, Mercier CE, Soll RF, Litt JS. Racial Inequity in High-Risk Infant Follow-Up Among Extremely Low Birth Weight Infants. Pediatrics. 2023 Feb 1;151(2):e2022057865. doi: 10.1542/peds.2022-057865. PMID: 36594226.
Hoffman ET, Uhl FE, Asarian L, Deng B, Becker C, Uriarte JJ, Downs I, Young B, Weiss DJ. Regional and disease specific human lung extracellular matrix composition. Biomaterials. 2023 Feb;293:121960. doi: 10.1016/j.biomaterials.2022.121960. Epub 2022 Dec 24. PMID: 36580718; PMCID: PMC9868084.
Infeld M, Wahlberg K, Cicero J, Plante TB, Meagher S, Novelli A, Habel N, Krishnan AM, Silverman DN, LeWinter MM, Lustgarten DL, Meyer M. Effect of Personalized Accelerated Pacing on Quality of Life, Physical Activity, and Atrial Fibrillation in Patients With Preclinical and Overt Heart Failure With Preserved Ejection Fraction: The myPACE Randomized Clinical Trial. JAMA Cardiol. 2023 Feb 1. doi: 10.1001/jamacardio.2022.5320. [Epub ahead of print.] PMID: 36723919.
Manning AR, Beck ES, Schindler MK, Nair G, Clark KA, Parvathaneni P, Reich DS, Shinohara RT, Solomon AJ. T1/T2 ratio from 3T MRI improves multiple sclerosis cortical lesion contrast. J Neuroimaging. 2023 Jan 30. doi: 10.1111/jon.13088. [Epub ahead of print.] PMID: 36715449.
McPartland JM, O'Sullivan SE. Origins of Cannabis sativa in Ireland and the Concept of Celtic Hemp: An Interdisciplinary Review. Cannabis Cannabinoid Res. 2023 Jan 23. doi: 10.1089/can.2022.0263. [Epub ahead of print.] PMID: 36695660.
Pulcini CD, Raphael JL, Lopez KN. Translating Research into Child Health Policy: Aligning Incentives and Building a New Discourse. Pediatr Clin North Am. 2023 Feb;70(1):151-164. doi: 10.1016/j.pcl.2022.09.012. PMID: 36402465.
Velasquez F, Dickson C, Kloc ML, Schneur CA, Barry JM, Holmes GL. Optogenetic modulation of hippocampal oscillations ameliorates spatial cognition and hippocampal dysrhythmia following early-life seizures. Neurobiol Dis. 2023 Jan 28;178:106021. doi: 10.1016/j.nbd.2023.106021. [Epub ahead of print.] PMID: 36720444.
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