Prachi Ghule, Ph.D., Assistant Professor
Cell cycle control of histone genes in human embryonic stem and induced pluripotent stem (iPS) cells. Subnuclear organization of cell cycle regulatory factors in Histone Locus Bodies. Molecular mechanisms of cell cycle control during early embryogenesis using HINFP knock-out mice.
Jonathan Gordon, Ph.D., Assistant Professor
Genomics of homeobox proteins, Runx2 and chromatin remodeling factors during osteogenesis. Profiling of lineage- selected cells during osteogenic differentiation using GFP mouse models. Bone-related regulatory networks and epigenetic mechanisms by high-throughput sequencing (DeepSeq).
Sayyed K. Zaidi, PhD, Associate Professor
Genetic and epigenetic regulation of cell proliferation and differentiation in relation to human leukemia. Mechanisms mediating infinite growth potential of human embryonic stem cells. Nuclear architecture and mitotic bookmarking in cancer cells.
Coralee Tye, Ph.D., Assistant Professor
Long noncoding RNAs (lncRNAs) in osteogenic differentiation of mesenchymal stromal cells. lncRNA regulation of cancer phenotype, with particular interest to lncRNAs involved in bone metastasis. Whole transcriptome sequencing (RNA-Seq).