LCOM & Department News

UVM Part of NIH Study of Rural South's Health & Longevity Challenges

May 22, 2019 by Jennifer Nachbur

(May 22, 2019) In an effort to understand why some people born in rural communities in the South live shorter and less healthy lives than their counterparts elsewhere in the same counties as well as across the country, researchers from the Larner College of Medicine at the University of Vermont at 11 other institutions will be participating in a new longitudinal cohort study aimed at combating this issue - the Risk Underlying Rural Areas Longitudinal Study (RURAL) .
(May 22, 2019) Why are some people born in the rural South less healthy and prone to die sooner?

In an effort to understand why some people born in rural communities in the South live shorter and less healthy lives than their counterparts elsewhere in the same counties as well as across the country, researchers from the Larner College of Medicine at the University of Vermont (UVM) today announced they will be participating in a new longitudinal cohort study aimed at combating this issue.

The Risk Underlying Rural Areas Longitudinal Study (RURAL) will allow researchers to learn what causes the high burden of heart, lung, blood and sleep (HLBS) disorders in Kentucky, Alabama, Mississippi and Louisiana and offer clues regarding how to alleviate them. 

With funding from the National Heart, Lung, and Blood Institute, part of the National Institutes of Health, this six-year, $21.4 million multi-site prospective cohort study will include 50 investigators from 15 other institutions, including UVM University Distinguished Professor of Pathology and Laboratory Medicine Russell Tracy, Ph.D., FAHA, ABCC.

To better understand why certain factors amplify risk in some rural counties and what renders some communities more resilient, the researchers will be recruiting and studying 4,000 multi-ethnic participants from 10 of the most economically disadvantaged rural counties in southern Appalachia and Mississippi Delta and parts of the rural South.

Using a self-contained mobile examination unit, ‘a research center on wheels,’ a transdisciplinary team will conduct an approximately four-hour detailed baseline examination on the study participants. Familial, lifestyle and behavioral factors, along with medical history including risk for HLBS disorders will be recorded. Environmental and economic factors will also be studied and standard and novel risk factors for HLBS disorders will be assayed. Investigators will use smart phones and wearable activity monitors in order to help collect health and lifestyle information of the participants.

“RURAL is a unique opportunity to work with participants in economically-challenged areas, people who have not had much opportunity to participate in NIH epidemiological studies,” says UVM’s Tracy, who has over 30 years of experience in population studies of heart disease, diabetes and other chronic diseases of aging, and currently directs a national-level biorepository at UVM with more than 4.5 million biosamples.

Tracy explains that UVM’s Laboratory for Clinical Biochemistry Research will help design the overall protocol, especially for the collection of biosamples, such as blood and urine. The lab will serve as the RURAL Biorepository, ultimately storing and making available hundreds of thousands of biosamples for future research. In addition, Tracy’s lab will also perform a variety of clinical and research measurements to help identify critical factors that determine better or worse health status in rural communities. 

“The rural health challenge in the South does not spare any race or ethnicity. These high risk and economically disadvantaged rural communities are vulnerable to clusters of multiple health problems,” explained Vasan Ramachandran, M.D., FAHA, FACC, principal investigator and Boston University director of the renowned Framingham Heart Study, with which he has been affiliated for more than 20 years. “We aim to understand the rural health challenge in the South and share our findings with and offer health education to these rural communities.”

The study coordinating center is Boston University School of Medicine (BUSM). Investigators from the University of Louisville (Kentucky), LSU’s Pennington Biomedical Research Center, University of Mississippi Medical Center and University of Alabama at Birmingham, will play a central role in participant recruitment, retention, follow-up, data return, return of results, community engagement and education.

UVM’s Larner College of Medicine is one of 12 institutions participating in RURAL. Other participating institutions are Duke University; Emory University; Johns Hopkins University; Los Angeles BioMedical Research Institute (UCLA); University of California, Berkeley; University of Massachusetts Medical School; University of North Carolina at Chapel Hill; Perelman School of Medicine at the University of Pennsylvania; University of Virginia at Charlottesville; and the Wake Forest School of Medicine. 

 

Past Department Highlights

Congratulations, to Dr. Jason Brazelton, M.D., for being named Physician of the Year by the Vermont Medical Society. "Dr. Brazelton's thoughtful and collabrative approach has improved care in our community and Porter's Medical staff has been incredibly fortunate to work with him." (09/2022)

Litele Cezar de Cruz, Ph.D., a visiting scholar from Brazil in the lab of Dr. Albert van der Vliet, Ph.D., and Nathaniel Shannon, a graduate student in the CMB program, in the lab of Dr. Brian Cunniff, Ph.D., based on their abstracts, have both received a Travel Award from SfRBM to attend the SfRBM Annual Meeting in Orlando later this year. https://sfrbm.org/meetings/2022-annual-conference/. In addition, Nate's abstract was selected to be presented as a talk at the conference. Chris Dustin, a former RBP Ph.D. student, and now a post-doc candidate at University of Pittsburg will also give an oral presentation at the conference. RBP is again well represented at this major conference in our field.

Research Day 2022, the fifth pathology research day was an incredible success. Thank you to the organizers Vice Chair for Research Dr. Mark Fung, M.D., Ph.D., Elizabeth Corteselli, Ph.D., post doctoral associate, Nate Shannon, CMB graduate student, and Dr. Rosemary Mattaino, M.D. Thank you as well to the presenters, and moderators for an engaging experience. Four sessions were held spanning the topics of: emerging technologies, and advances in knowledge using new technologies, a panel discussion on having a well-balanced academic career, and presentations from trainees, and internal award recipients. A well attended reception was help in the Hoehl Gallery after the event. (09/2022)

Research Day organizers - 2

(Dr. Fung, M.D., Ph.D., Elizabeth Corteselli, Ph.D., Nate Shannon, Dr. Janssen-Heininger, Ph.D.,)

Yvonne Janssen-Heininger, Ph.D., professor of pathology and laboratory medicine, has received a two-year, $200,000 Lung Cancer Discovery Award from the American Lung Association (ALA). The grant will support her research project, titled "Glutaredoxin, Glutathione Metabolism and Lung Cancer." According to the ALA, "The Lung Cancer Discovery Award is for highly meritorious research projects with the potential to significantly improve and transform diagnostic and therapeutic paradigms; foster innovation, use novel approaches; and/or accelerate progress in lung cancer research that improves patient care and helps save lives." (08/2022)

Congratulations to Dr. Christina Wojewoda on her acceptance, as a Master Teacher, into the Larner College of Medicine Teaching Academy. (8/2022)

Congratulations to Dr. Alex Kaloff on receiving The University of Vermont Medical Center Leadership Award for the second quarter of 2022. (7/2022)

Congratulations to Dr. Rebecca Wilcox on being selected as a member of the 2022-2023 class of fellows participating in the Hedwig van Ameringen Executive Leadership in Academic Medicine® (ELAM) Program at Drexel University College of Medicine. Read more (06/2022)

Dr. Elizabeth Corteselli, a post-doctoral fellow in our department and trainee on the VLC T32 training program, is the recipient of a prestigious Parker B. Francis Fellowship Award. She will be recognized during a reception at the ATS conference in San Francisco this coming week. Congratulations Elizabeth! (05/2022)

Yvonne Janssen-Heininger, Ph.D., professor of pathology and laboratory medicine has been recognized by the Provost and Senior Vice-President for the university of Vermont Distinguished Professor recognition. This recognition is reserved for the most prominent faculty members who have made outstanding contributions to advancing knowledge in their disciplines. This is a significant honor for Dr. Janssen-Heininger. This accolade will be awarded during the spring 2022 UVM Commencement ceremony. Congratulations!! (05/2022)

Dr. Mount and Dr. Threlkeld won a Stout award at USCAP, a Stout award recognizes and awards an individual for the best English language peer-reviewed paper published, which resolves scientific medical problems by studying the anatomic features. Congrats to both! Read paper here: Arch Pathol Lab Med. 2021 May 1 (04/2022)

Congratulations! Jo Conant, M.D. has received the ‘Gender Equity in Medicine and Science Rising Star’ award. This award recognizes a woman or gender minority* faculty or staff member at the Larner College of Medicine who is in the early stage of their career, and who demonstrates excellence in contributions to students, colleagues, and/or the institution in the areas of gender equity and inclusion through service, program development, teaching, research or beyond. The awardee also shows the promise for future contributions and leadership in their field as well as in achieving goals for the advancement of diversity, equity, and inclusion. (02/2022)

LCOM class of 2024 Foundations Awards, Winners and nominees from our Department: Dr. Rebecca Wilcox- nominated for the AMWA Gender Equity Award | nominated for the Foundations Teaching Award; Dr. Pam Gibson– awarded the Silver Stethoscope Award | nominated for the Foundations Teaching Award | nominated for the Dean Warshaw Integration Award; Dr. Jo Conant– nominated for the Silver Stethoscope Award | nominated for the Dean Warshaw Integration Award; Medical Student Matt Hodd-Wells awarded the Ephraim Woll Award for Excellence in General Pathology (01/2022)

Congratulations! Dr. Rebecca Wilcox, M.D. has been appointed Associate Dean for Faculty Affairs at the Larner College of Medicine. Read her story. (01/2022)

Congratulations! Dr. Yvonne Janssen-Heininger, Ph.D.– Dean’s Research Laureate Award (Professor) Dr. Yvonne Janssen-Heininger was presented the Dean’s Research Laureate Award on 10/27/2021 at the LCOM State of Research Address and Awards. Please see the PDF slide that was presented at the program. (10/2021)

Heading to clinical trials..."UVM researchers celebrate ‘first-of-its-kind’ mesothelioma treatment headed to clinical trials" – My Champlain Valley News.  University of Vermont researchers have made a breakthrough in their study of possible treatments for malignant mesothelioma, a rare and aggressive cancer linked to asbestos exposure. (10/2021)

Terri Messier, research analyst and lab manager for the Cunniff lab, has been highlighted in the "Meet the Staff" section of the the Larner College of Medicine Dean's Newsletter, October 20, 2021 | Volume III, Issue 20. (10/2021)

Congratulations! Albert van der Vliet, Ph.D. has been named a 2021 Fellow of the Society for Redox Biology and Medicine. SfRBM annually confers the special title of Fellow to members who have made outstanding contributions to the association as well as in the field of free radical chemistry, redox biology and antioxidants. (09/2021)

Well done! Christina Wojewoda, M.D., associate professor of pathology and laboratory medicine, has received, along with her colleague Daniel Rhoads, M.D., of the Cleveland Clinic, the 2021 College of American Pathologists (CAP) Laboratory Improvement Programs Service Award. The award honors an individual(s) serving within the ranks of the CAP Council on Scientific Affairs who has demonstrated exceptional service. The two pathologists serve as chair and vice chair, respectively, of the CAP microbiology committee. (08/2021)

Congratulations to Dr. Yvonne Janssen-Heininger, Dr. Albert van der Vliet, Dr. David Seward and their team members for this outstanding acknowledgement (see pdf) from the The American Physiological Society; "your article has been selected for APSselect  (http://apsselect.physiology.org/),  a collection from the APS that showcases some of the best recently published articles in physiological research." (7/2021)

2020-2021 Teaching Award This award is nominated for and voted by medical resdients for idividuals going above and beyond for resident education. Nominees this year: Dr. Agnes Balla, Dr. Kelly Butnor, Dr. Rebecca Wilcox and Dr. Bronwyn Bryant. The winner this year is Dr. Agnes Balla. (06/2021)

Dr. Joanna Conant has become a member of The Teaching Academy at Robert Larner, M.D. College of Medicine at the University of Vermont. The Teaching Academy sustains and supports an interdisciplinary community of educators who value the scholarship of teaching and learning while facilitating educator development; improve the efficiency and quality of medical education through collaboration and scholarship; and promote an academic environment that increases the value and impact of educators locally, regionally, and nationally.Congrats to Jo on this achievement! (06/2021)

Congratulations to Dr. Arti Shukla on receiving the SAASCR 2021 Outstanding Achievement Award for her seminal contributions to the field of cancer research. Well done Arti!! (5/2021)

SAASCR award 2021

Congratulations!  To Pam Gibson, M.D. who has been awarded 2021 Gender Equity Champion Award which honors Larner College of Medicine community members (faculty, staff or students) who have demonstrated outstanding commitment and service to the advancement of women and those with underrepresented gender identities beyond the scope of their job, area of research, or training. Also, to Joanna Conant, M.D. on her nomination for 2021 The Rising Star Emerging Professional Award which honors a Larner College of Medicine woman or gender minority faculty or staff member who is in the early stage of their career, and who demonstrates excellence in contributions to students, colleagues, and/or the institution in the areas of gender equity and inclusion through service, program development, teaching, research or beyond. (02/2021)

LCOM Foundations Awards: Congratulations to Ron Bryant, M.D. on receiving the Foundations Teaching Award which recognizes the faculty member who provided the most outstanding teaching activities within the foundations curriculum. Also, congratulations to award nominees: Pam Gibson, M.D. for both the Above and Beyond Award and the AMWA Gender Equity Award; Andrew Goodwin, M.D. and Christina Wojewoda, M.D. for the Silver Stethoscope Award and Rebecca Wilcox, M.D. for the Dean Warshaw Integration Award. (01/2021)

LCOM Teaching Academy Recognition for P&LM faculty: Deborah Cook, M.D. and Anne Stowman, M.D. were inducted as Master Teachers and Rebecca Wilcox, M.D. was inducted as a Distinguished Educator. (01/2021)

Mark Fung, M.D., Professor, Pathology and Laboratory Medicine, has been elected as a new Trustee of the American Board of Pathology. His 3-year term will begin January 2021. Read about it here. (12/2020)

Sarah A. Nowak, PhD, Assistant Professor, Department of Pathology and Laboratory Medicine, Larner College of Medicine was named the inaugural Blodwen S. Huber Early Career Green and Gold Professor in Pathology and Laboratory Medicine. (12/2020)

David J. Seward, MD, PhD, Assistant Professor, Department of Pathology and Laboratory Medicine, Larner College of Medicine was named the inaugural Elmer R. Huber Early Career Green and Gold Professor in Pathology and Laboratory Medicine. (12/2020)

Terri Messier, Research Analyst and Lab Manager of the Cunniff lab was recently awarded a Dean's Excellence in Research Award from the Larner College of Medicine. Terri has served the UVM community for over 25 years both as a scientist and steward of professionalism. Congratulations Terri!! (11/2020)

Congratulations to Dr. Yvonne Janssen-Heininger, Ph.D. on her selection as a new Fellow of the Society for Redox Biology and Medicine (SfRBM) in recognition of her outstanding contributions in the field of redox biology and to SfRBM. (09/2020)

Congratulations to Dr. Joanna Conant, M.D. on her acceptance into the Teaching Academy's Medical Education Fellowship Program. Only 8-10 faculty from across the Larner College of Medicine are selected for participation in the program. Well done, Jo! (08/2020)

Associate Professor, Dr. Laura Greene, MD, has been appointed Interim Assistant Dean for Admissions for the Larner College of Medicine. (08/2020)

Congratulations to Bei Zhang, MD, PhD, Associate Professor, the newest graduate of the Medical Education Fellowship Program. The cohort style program is for Larner College of Medicine educators who seek additional preparation for teaching across the medical education continuum. (07/2020)

UVM Health Network’s Genomic Medicine Program is highlighted in the recent issue of Vermont Medicine Magazine, read it here. (05/2020)

Department efforts in COVID-19 research & testing are ongoing at UVM LCOM and the UVM Medical Center. The Rutland Herald/Times Argus ran the following story on these efforts. Teamwork & Testing (04/2020)