Nikon STORM Super-Resolution Microscope


                                        Super Resolution Microscope     Annexin 5 staining on trophoblasts






Nikon N-STORM super-resolution microscope system consisting of a Nikon Ti-E TIRF inverted microscope base with laser modules delivering excitation at 405 nm, 488 nm, 561 nm, and 647 nm, and a high sensitivity Andor iXON3 DU897 EMCCD camera. This instrument provides resolution in the fluorescence mode of 20 nm lateral and 50 nm axial. Both fixed and live cell preparations can be imaged, as well as imaging in three dimensions.

Papers published from the MIC:

  • Clemments, A. M., et al. (2017). "Spatial Mapping of Protein Adsorption on Mesoporous Silica Nanoparticles by Stochastic Optical Reconstruction Microscopy." J Am Chem Soc 139(11): 3978-3981.
  • Lombardo, A. T., et al. (2017). "Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro." Nat Commun 8: 15692.
  • Lombardo, A. T., et al. (2019). "Myosin Va transport of liposomes in three-dimensional actin networks is modulated by actin filament density, position, and polarity." Proc Natl Acad Sci U S A 116(17): 8326-8335.

Additional publications located here.